ncRNA name | GPR91 shRNA |
ncRNA Category | shRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | shRNA injection, immunofluorescence, qRT-PCR, Western blot, ELISA, luciferase reporter assay, CHIP assay |
Expression pattern | associated |
Functional description | Treatment with GPR91 shRNA attenuated the retinal avascular area, abnormal neovascularization and pericyte loss. |
PubMed ID | 28374767 |
Year | 2017 |
Title | Transcription factors regulate GPR91-mediated expression of VEGF in hypoxia-induced retinopathy. |
Drug-related ncRNA | NA |
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